Advanced Ultrasound in Diagnosis and Therapy ›› 2024, Vol. 8 ›› Issue (2): 41-48.doi: 10.37015/AUDT.2024.230043
• Review Articles • Previous Articles Next Articles
Hao Feng, MMa,1, Yaqin Sun, MMb,1, Jingjing Zhang, MMa, Jiajia Wang, MMa, Shuai Han, MMa, Shumin Wang, PhDa,*(
)
Received:2023-09-10
Accepted:2024-02-11
Online:2024-06-30
Published:2024-07-01
Contact:
Department of Ultrasonography, Peking University Third Hospital, No. 49 Huayuan North Road, Haidian Dist, Beijing, China,e-mail: About author:1 Hao Feng and Yaqin Sun contributed equally to this study.
Hao Feng, MM, Yaqin Sun, MM, Jingjing Zhang, MM, Jiajia Wang, MM, Shuai Han, MM, Shumin Wang, PhD. Ultrasound Assessment of Effect of Maternal Thyroid Function During Pregnancy on Fetal and Neonatal Bone Development. Advanced Ultrasound in Diagnosis and Therapy, 2024, 8(2): 41-48.
Table 1
The effect of abnormal maternal thyroid function during pregnancy on fetal and neonatal thyroid and bone maturation and its characterization by ultrasound"
| Maternal thyroid abnormalities during pregnancy | Fetal and neonatal thyroid abnormalities | Thyroid sonograms | Bone maturation sonograms |
|---|---|---|---|
| Maternal Hyperthyroidism | Hyperthyroidism | Hyperthyroid goiter | Accelerated bone maturation: The presence of DFE before 31 weeks |
| CDFI: Central vascularization | |||
| Hypothyroidism | Hypothyroid goiter | Delayed bone maturation: The absence of DFE after 33 weeks) | |
| CDFI: Peripheral vascularization |
Figure 5
Sonographic findings of hand and wrist in patients of various ages (girls in this figure). (A) Sketch maps of the distal radius and ulna, metacarpal and phalanx. The epiphysis is delineated by a dotted line. The hyper-echoic surface of ossification center and the cortex of the diaphysis are delineated by solid lines; (B) Sonographic findings for radius, ulna, metacarpals and phalanx; the dotted lines represent measurements of the diameters of the epiphysis and ossification center. d/ D = ratio of the diameter of the ossification center to that of the epiphysis. The value of d/D was 0% when no ossification center emerged and 100% when the ossification center fused with the diaphysis and no hypo-echoic epiphyseal plate between them could be identified. DDia, diaphysis; Epi, epiphysis; MC, metacarpal; Med, medial; MP, middle phalanx; Ossi, ossification center; PP, primary phalanx."
Table 2
Assessing indicators for bone development by ultrasound"
| Bone development | Assessment indicators by ultrasound |
|---|---|
| Secondary center of ossification | Early or delayed emergence |
| Volume | |
| Ossification Ratios: Length ratio of ossification center to epiphysis | |
| Epiphysis | SWI: Evaluation of epiphyseal blood flow |
| Bone properties | QUS: reflects several bone properties, including microarchitecture, bone mineral content, density, elasticity, cortical thickness, and strength |
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