Research Progress in Ultrasonic Regulation of Cholinergic Anti-inflammatory Pathway

doi:10.37015/AUDT.2022.200034

Abstract

Abstract:

The cholinergic anti-inflammatory pathway is a neuro-immune regulatory pathway that mediates anti-inflammatory effects based on the vagus nerve, acetylcholine and α7 nicotinic acetylcholine receptors. In recent years, the effect of nerve stimulation by ultrasound has attracted much attention and has been widely studied. Ultrasound can stimulate the vagus nerve or spleen nerve and activate the cholinergic anti-inflammatory pathway, exerting anti-inflammatory and organ protection effects, which is expected to provide a new treatment for many inflammatory diseases. The purpose of this review is to introduce the composition, mechanisms and regulation methods of cholinergic anti-inflammatory pathway, and discuss its therapeutic implications.

Key words: Ultrasound; Vagus nerve; The cholinergic anti-inflammatory pathway; α7 nicotinic acetylcholine receptors

Wuqi Zhou, MD, Yishu Song, MD, Rui Wang, MD, Qiaofeng Jin, MD, Mingxing Xie, PhD, Li Zhang, PhD. Research Progress in Ultrasonic Regulation of Cholinergic Anti-inflammatory Pathway. Advanced Ultrasound in Diagnosis and Therapy, 2022, 6(4): 147-152.

Figures/Tables 2

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