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Tietze Syndrome in A Female POST-COVID-19 Infection: A Review of Current Understanding and Ultrasound Diagnosis
Sun Yang, Li Mofan, Wang Shumin
Advanced Ultrasound in Diagnosis and Therapy    2025, 9 (2): 215-218.   DOI: 10.37015/AUDT.2025.240029
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Tietze syndrome which refers to painful non-purulent inflammation of the costal cartilage or sternoclavicular joint is a rare disease that is poorly reported. We report a case of Tietze syndrome in a 52-year-old female with sternoclavicular joint pain and chest wall mass post-COVID-19 virus infection. She suffered pain and swelling in the left sternoclavicular joint, which were relieved after hot compress. This case is the first report on Tietze syndrome post-COVID-19 virus infection in China. We report this case to improve our understanding of this disease and discuss possible mechanism from the perspective of embryology and pathology.

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Glomus Tumor of the Female Vulva: A Case Report and Review
Liu Xinyu, Yuan Yinuo, Meng Yao, Zhang Wenjing, Xu Huimin, Zhang Jinrui, Liu Cun
Advanced Ultrasound in Diagnosis and Therapy    2025, 9 (2): 219-223.   DOI: 10.37015/AUDT.2025.240035
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Glomus tumor is a benign, subcutaneous neoplasm that typically arises in regions abundant in glomus bodies, manifesting as a painful nodule. Currently, perineal glomus tumors are rarely reported in the literature. Herein, we present a unique case of glomus tumor originating in the perineal region. Ultrasound examination revealed a heterogeneous mass within the subcutaneous soft tissue layer of the vulva, featuring a distinct boundary and peripheral blood flow signals. The ultrasound contrast imaging of this mass demonstrated rapid peripheral ring enhancement during the arterial phase, followed by a gradual inward perfusion from the periphery towards the center of the nodule-like or branching-like structure, exhibiting concentric enhancement. The internal portion of the nodule showed low enhancement, which progressively diminished during the venous and delayed phases. Subsequently, an ultrasound-guided biopsy confirmed the diagnosis of glomus tumor, and the patient underwent successful surgical treatment.

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Imaging Diagnosis of Neonatal Umbilical Arteriovenous Malformation Complicated with Portosystemic Shunt
Zhang Minyu, Jia Baocheng, Huang Liuming
Advanced Ultrasound in Diagnosis and Therapy    2025, 9 (2): 224-227.   DOI: 10.37015/AUDT.2025.240012
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In the last twenty years, there were less than 10 cases of umbilical arteriovenous malformations have been reported, which usually had single complication, included mild cardiac dilatation, pulmonary hypertension, hemorrhagic shock, and hepatic damage. Unlike previous cases, we report a case of neonate multiple organ failure caused by umbilical arteriovenous malformation complicated with portosystemic shunt, which was diagnosed by ultrasound and arteriography. We provide a new insight that umbilical arteriovenous malformation and portosystemic shunt should be considered in neonates with unexplained multiple organ failure, for researching the cause of neonate multiple organ failure, especially in those with right heart overload, hyperammonemia, and liver dysfunction. A targeted and comprehensive Dopler ultrasound can make a definitive diagnosis as soon as possible.

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The Diagnostic Pitfall of Lymphadenopathy: Ultrasonic Imaging Findings in a Case of Cat Scratch Lymphadenitis
Li Tiantian, Zhu Miao, Shen Dejuan, Qian Xiaoqin
Advanced Ultrasound in Diagnosis and Therapy    2025, 9 (1): 92-95.   DOI: 10.37015/AUDT.2025.230053
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Lymphadenopathy is a common clinical disease, and ultrasonography is its primary preliminary diagnostic screening strategy. With an increase in house-raised pets, the annual incidence of cat scratch lymphadenitis is rising. After infection, the characteristics of the disease include abnormal lymph node enlargement in the local drainage, accompanied by low heat sweats, similar to clinical symptoms of malignant disease. The two-dimensional ultrasound results lack specificity. However, garland-like variation can be observed in the enhanced images, which can be used for the differential diagnosis of cat scratch lymphadenitis. In this case, we obtained the ultrasound and computed tomography images of a patient with cat scratch lymphadenitis and compared and analyzed them with the pathological data.

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Gastroduodenal Intussusception Due to a Gastric Gastrointestinal Stromal Tumor in Adult from Sonographer's Perspective
Ge Xifeng, Liu Wenzheng, Chen Wen, Mei Fang, Cui Ligang
Advanced Ultrasound in Diagnosis and Therapy    2024, 8 (4): 255-258.   DOI: 10.37015/AUDT.2024.230048
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A gastric GIST which causes gastroduodenal intussusception is rare. A Pubmed search only identified 21 published cases of gastroduodenal intussusception due to gastric GIST. Only 2 of them mentioned ultrasound without further analysis. Here, we report a case of gastroduodenal intussusception due to a gastric GIST with multiple imaging especially ultrasound. A 72-year-old Chinese woman was admitted to hospital because of epigastric pain, black stool lasting and occasional vomiting for 2 months. She underwent abdominal ultrasound, endoscopy, and contrast enhanced CT in turn. Abdominal ultrasound revealed a hypoechoic, medium-sized lesion beside pancreatic head. Endoscopy showed a submucosal lesion of gastric fundus overlapping into duodenum. The lesion manifested slight enhancement in the arterial phase on enhanced CT scans. The patient underwent laparoscopic exploration and partial gastrectomy. The histological examination revealed a low-risk gastric GIST of spindle-shaped cell type.

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Multimodal Sonographic Findings of Embryonal Carcinoma in the Testis: A Case Report and Literature Review
Guiwu Chen, MS, Zhizhong He, BS, Wenqin Liu, MS, Junjun Chen, BS, Xiaomin Liao, MS, Yuhuan Xie, BS
Advanced Ultrasound in Diagnosis and Therapy    2024, 8 (2): 74-77.   DOI: 10.37015/AUDT.2024.220046
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Pure embryonal carcinoma (EC) is a rare malignant tumor that primarily occurs in infants with a sex development disorder and adults aged in their thirties to forties. This tumor behaves more aggressively than other germ cell tumors in the testis, and most of them should undergo surgery or chemotherapy. However, only a few case reports have involved imaging, and most of them are limited. Here, we present a case of pure EC in the testis of a 27-year-old male with multimodal ultrasonography, computed tomography, and magnetic resonance imaging.

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Open Access, Peer-reviewed

ISSN 2576-2516 (Online)

ISSN 2576-2508 (Print)

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