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Advanced Ultrasound in Diagnosis and Therapy ›› 2026, Vol. 10 ›› Issue (1): 69-73.doi: 10.26599/AUDT.2026.250060

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  • 收稿日期:2025-07-17 修回日期:2025-09-05 接受日期:2025-10-18 出版日期:2026-03-31 发布日期:2026-03-30

The Effects of Ajwa Dates Consumption (Phoenix dactylifera L), on Ovarian Follicular Features with Transvaginal Ultrasound in Perimenopausal Women

Syahril Erlina, Abdullah Nusratuddinb, Ilyas Muhammadc, As’ad Suryanid, Choridah Linae, Natzir Rosdianaf, Kurniawan Liong Boyg, Bahar Burhanuddinh, Mappaware Nasrudin A.i,*(), Mulyadi Farah Ekawatij, Yacca Susdiaman Sudink   

  1. aDepartment of Radiology, Universitas Muslim Indonesia, Makassar, Indonesia
    bDepartment of Obstetric and Gynecology, Hasanuddin University, Makassar, Indonesia
    cDepartment of Radiology, Hasanuddin University, Makassar, Indonesia
    dDepartment of Clinical Nutrition, University of Hasanuddin, Makassar, Indonesia
    eDepartment of Radiology, Gajah Mada University, Yogyakarta, Indonesia
    fDepartment of Biochemistry, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia
    gDepartment of Clinical Pathology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia
    hFaculty of Medicine, Hasanuddin University, Makassar, Indonesia
    iDepartment of Obstetrics and Gynecology, Faculty of Medicine, Universitas Muslim Indonesia, Makassar, Indonesia
    jDepartment of Physiology, Faculty of Medicine, Universitas Muslim Indonesia, Makassar, Indonesia
    kFaculty of Medicine, Universitas Muslim Indonesia, Makassar, Indonesia
  • Received:2025-07-17 Revised:2025-09-05 Accepted:2025-10-18 Online:2026-03-31 Published:2026-03-30
  • Contact: Faculty of Medicine Universitas Muslim Indonesia, Makassar, Indonesia, Urip Sumoharjo Street No.KM. 5, Makassar, South Sulawesi. (Erlin Syahril), e-mail: nasrudin.nasrudin@umi.ac.id

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Abstract:

Objective Perimenopause is the transition from the reproductive period to menopause, marked by a decline in the number and function of oocytes. Transvaginal ultrasound is a reliable method for assessing ovarian reserve. Ajwa dates (Phoenix dactylifera L.) contain macro- and micronutrients, phenolics, and flavonoids, which have antioxidant potential that may improve ovarian condition in perimenopausal women. This study aims to determine the effect of ajwa date consumption on ovarian follicle characteristics assessed by transvaginal ultrasound in perimenopausal women.

Methods This quasi-experimental pre-post control group study was conducted at RSIA Sitti Khadijah I Muhammadiyah Makassar, Indonesia, from February to August 2023. A total of 44 perimenopausal women aged 42-48 years were randomly assigned to intervention (n = 28) or control groups (n = 16). Ovarian follicle changes were analyzed using the Mann-Whitney U test.

Results The intervention group showed a decrease in follicle number with an increase in follicle size, while the control group showed an increase in follicle number and a decrease in size. These differences were statistically significant (P < 0.05).

Conclusion Consumption of ajwa dates as an exogenous antioxidant can influence the number and size of antral follicles, which serve as predictive indicators of menopausal transition.

Key words: Ajwa dates, Antral follicle, Perimenopause, Transvaginal ultrasound

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GroupNumber of follicles aAverage Δ number of follicles aP value b
BeforeAfter
a Mean ± Deviation standard, b Mann - whitney U-test
Intervention10.11 ± 2.185.96 ± 1.99↓ 4.14 ± 2.27
< 0.001
Control9.31 ± 2.7311.44 ± 3.46↑ 2.12 ± 3.5

"

GroupSize of follicles (cm) aAverage Δ size of follicles (cm) aP value b
BeforeAfter
a Mean ± Deviation standard, b Mann-whitney U-test
Intervention0.55 ± 0.150.76 ± 0.18↑ 0.21 ± 0.20
0.014
Control0.74 ± 0.390.73 ± 0.29↓ 0.01 ± 0.46
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